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Cross-Sectional Serological Survey of Human Fascioliasis in Haiti

机译:海地人筋膜炎横断面血清学调查

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摘要

Fasciola hepatica, the aetiological agent of fascioliasis in the Caribbean region, occurs throughout the major islands of the Greater Antilles and in localised zones on two islands (Martinique and Saint Lucia) of the Lesser Antilles. However, apart from Puerto Rico, information regarding human fascioliasis in islands of the Caribbean is out of date or unavailable, or even nonexistent as in Haiti. The authors conducted a retrospective, cross-sectional serological survey in Port-au-Prince using a Western blotting test (LDBIO Diagnostics) on human fascioliasis in Haiti. A total of 216 serum samples obtained from apparently healthy adults were tested. The frequency of antibodies in serum samples of the study population was 6.5% (14/216). The immunodominant bands recognised in Western blots were 27-28 kDa (100%), 42 kDa (64%), 60 kDa, and 8-9 kDa (28%). This is the first survey to reveal a relatively low proportion of asymptomatic F. hepatica-infected humans in Haiti.
机译:肝片筋膜炎的病原体是Fasciola hepatica,它分布在整个大安的列斯群岛的主要岛屿以及小安的列斯群岛的两个岛屿(马提尼克岛和圣卢西亚)的局部区域。但是,除了波多黎各以外,关于加勒比海岛屿的人筋膜病的信息已经过时或不可用,甚至像海地一样不存在。作者在太子港进行了回顾性横断面血清学调查,使用了针对海地人筋膜病的蛋白质印迹试验(LDBIO Diagnostics)。检验了从显然健康的成年人身上获得的216个血清样本。研究人群血清样本中抗体的频率为6.5%(14/216)。在蛋白质印迹中识别的免疫显性条带为27-28 kDa(100%),42 kDa(64%),60 kDa和8-9 kDa(28%)。这是首次发现海地无症状肝炎链球菌感染者比例相对较低的调查。

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